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P. variotii can cause paecilomycosis. Linked to wood-trimmers disease and humidifier associated illnesses (17). Some members of this genus are reported to cause pneumonia.
It may produce arsine gas if growing on arsenic substrate. (3). This can occur on wallpapers covered with paris green (3).
They are reported to allergenic (7).
Commonly found in soil and dust, less frequently in air (17).